EFFICACY AND SAFETY OF CONVENTIONAL EPIDURAL VERSUS COMBINED SPINAL EPIDURAL IN PERCUTANEOUS NEPHROLITHOTOMY: A PROSPECTIVE AND RANDOMIZED CLINICAL STUDY

Objectives: The aim of the study was to compare efficacy and safety conventional epidural (ED) versus combined spinal (CSE) in percutaneous nephrolithotomy (PCNL) with addition opiods dexmedetomidine. Methods: This prospective, randomized, double-blinded clinical conducted patients undergoing PCNL. Group CSE had received anesthesia ED given anesthesia. Time first rescue analgesic total dose along hemodynamic parameters were compared up 24 h. Patient, surgeon satisfaction score, post-operative complications also compared. Results: from onset sensory block requirement analgesia prolonged group (218.4±18.30 min) as (210±17.88 min). (p<0.001) Mean time for postoperatively highly significant (2.42±0.49) (2.08±0.28). (p<0.0001) Total levobupivacaine required high (49.66±7.02) (45.66±3.12). In ED, score good 20 (44.44%) which significant. CSE, excellent 41 (91.1%) Post-operative both comparable (p>0.05). Conclusion: concluded that though techniques are safe efficient each having its own benefits. proven superiority over technique.